








RESILIENT & FOCUSED BUNDLE
Targeted support for a sharp mind and a resilient immune system – two formulas that work together to support your gut-brain axis.

MEMORY

MENTAL FOCUS

GUT BALANCE

IMMUNE SUPPORT
- Brain & Cognition for mental clarity, memory and focus – with omega 3 DHA, key B vitamins and brain-protective antioxidants
- Gut & Immunity for a healthy, balanced gut microbiome and stronger everyday immune defences
- Both designed for adults 50+, based on the science of ageing and UK nutrition research
The gut and brain are in constant communication – via what scientists call the gut-brain axis – which means what happens in one tends to affect the other. A balanced gut microbiome supports both nutrient absorption for a healthy brain, and friendly bacteria that support mood and mental focus.
After 50, both systems come under more pressure. Natural changes in gut bacteria can upset digestion and knock immunity. At the same time, the brain becomes more dependent on a consistent supply of nutrients like DHA, B vitamins and iron – precisely the ones that UK data shows many over-50s aren't getting enough of.
This supplement bundle supports both in a simple daily routine to help keep you comfortable, resilient to infection and mentally sharp.
Brain & Cognition
Supports mental clarity and a healthy brain – with omega 3 fatty acid DHA (docosahexaenoic acid) in a daily softgel. DHA is a key building block for brain structure that needs constant replacement and replenishment from our diets. A second daily capsule has key nutrients for cognitive function and mental performance that often fall short in the diets of adults 50+, including pantothenic acid (vitamin B5), iron, iodine and zinc.
Psychological and nervous system support – B vitamins, magnesium and L-methyl folate support the nervous system and normal psychological function, playing a role in mood, mental wellbeing, and coordinating bodily movement and sensation.
Protects brain cells from daily damage – with antioxidants including vitamin E and selenium, along with polyphenols from green tea and grape seed, to help protect the brain from damage caused by oxidative stress, which increases as we age.
Supports nutrient absorption – with easy-to-absorb mineral forms, plus Bioperine®, a patented black pepper extract shown to increase the absorption of vitamins and minerals, which can become harder for the older gut.
Gut & Immunity
Maintains a healthy digestion with a balanced gut microbiome – with 14 strains of live bacterial cultures including Lactobacillus and Bifidobacterium, to encourage a healthy, regular digestion and a diverse microbiome. Two billion colony-forming units (CFUs) in every daily capsule.
Strengthens your body’s natural defences – About 70 percent of your immune system is in your gut. Gut & Immunity supports it with both a blend of friendly live bacteria and immune-supporting nutrients often missing from 50+ diets – including iron, vitamins D and C and selenium.
Supports nutrient absorption – with easy-to-absorb mineral forms plus Bioperine®.
Brain & Cognition – one capsule and one softgel daily, preferably together, with a cold drink at mealtimes. 28 capsules and 28 softgels per pack, 28-day supply.
Gut & Immunity – one capsule per day with a cold drink at mealtimes. 28 capsules per pack, 28-day supply. Suitable for vegans and vegetarians. Gluten-free.
Brain and Cognition
| Ingredient | Per capsule | % NRV* |
|---|---|---|
| Vitamin D3 | 20µg (800 IU) | 400% |
| Vitamin E | 26mg (ɑ-TE)# | 217% |
| Vitamin C | 80mg | 100% |
| Vitamin B1 (Thiamin) | 5mg | 455% |
| Vitamin B2 (Riboflavin) | 4.2mg | 300% |
| Vitamin B3 (Niacin) | 16mg (NE)# | 100% |
| Vitamin B6 | 10mg | 571% |
| Folic Acid | 200µg | 100% |
| Folate | 50µg | 25% |
| Vitamin B12 | 25µg | 1000% |
| Pantothenic Acid (vitamin B5) | 21mg | 350% |
| Magnesium | 60mg | 16% |
| Iron | 7mg | 50% |
| Zinc | 15mg | 150% |
| Copper | 1mg | 100% |
| Manganese | 2mg | 100% |
| Selenium | 110µg | 200% |
| Chromium | 40µg | 100% |
| Iodine | 150µg | 100 |
| Carnitine | 10mg | N/A |
| N-Acetyl L-Cysteine | 10mg | N/A |
| Grape Seed Extract | 25mg | N/A |
| Green Tea Extract 4:1 | 20mg | N/A |
| Co-Enzyme Q10 | 10mg | N/A |
| BioPerine® Black Pepper Extract |
3mg | N/A |
| Ingredient | Per softgel | % NRV* |
|---|---|---|
| Fish Oil of which Omega 3 including EPA including DHA |
500mg 300mg 30mg 200mg |
N/A |
| Vitamin E | 6mg (α-TE)# | 50% |
* Nutrient Reference Value #a-TE: alpha-Tocopherol Equivalent; NE: Niacin Equivalent
CAPSULE: Magnesium Oxide, Capsule Shell (Hydroxypropyl Methylcellulose), Vitamin C (Ascorbic Acid), Vitamin E (D-Alpha Tocopherol Acid Succinate), Pantothenic Acid (Calcium Pantothenate), Grape Seed (Vitis vinifera) Extract (Maltodextrin), Green Tea (Camellia sinensis) Extract, Zinc Oxide, Ferrous Fumarate, Vitamin B3 (Nicotinamide), N-Acetyl L-Carnitine Hydrochloride, Anticaking Agents (Tricalcium Phosphate, Magnesium Stearate), Vitamin B6 (Pyridoxine Hydrochloride), Vitamin D3 Prep (Cholecalciferol), Co-Enzyme Q10, N-Acetyl L-Cysteine, Thiamin (Thiamin Hydrochloride), Ferrous Citrate, Riboflavin, Manganese Citrate, Manganese Sulphate, BioPerine® Black Pepper (Piper nigrum) Extract, Copper Sulphate, Copper Citrate, Folic Acid, Sodium Selenite, Chromium Chloride, Potassium Iodide, 5-Methyltetrahydrofolic Acid, Vitamin B12 (Methylcobalamin).
SOFTGEL: Fish Oil, Capsule Shell (Bovine Gelatin, Glycerol), vitamin E (DL-a- Tocopheryl Acetate).
Gut and Immunity
| Ingredient | Per tablet | % NRV* |
|---|---|---|
| Vitamin A | 400µg (RE) | 50% |
| Vitamin D2 | 20µg (800IU) | 400% |
| Vitamin C | 40mg | 50% |
| Vitamin B6 | 1.4mg | 100% |
| Folic Acid | 200µg | 100% |
| Folate | 50µg | 25% |
| Vitamin B12 | 25µg | 1000% |
| Calcium | 120mg | 15% |
| Iron | 3mg | 21% |
| Copper | 1mg | 100% |
| Selenium | 110µg | 200% |
| Chromium | 30µg | 75% |
| BioPerine® Black Pepper Extract | 3mg | N/A |
| Synbalance® Multi Strain live Bacteria Blend | 2 Billion (2 x 109 CFU) | N/A |
* Nutrient Reference Value
Manufactured in a GMP (Good Manufacturing Practice) facility in the UK
Calcium Carbonate, SynBalance® Multi Strain Live Culture Blend (Bifidobacterium lactis, Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus acidophilus, Bifidobacterium breve, Lactobacillus casei, Bifidobacterium bifidum, Bifidobacterium infantis, Bifidobacterium longum, Lactobacillus bulgaricus, Lactobacillus reuteri, Lactobacillus salivarius, Lactobacillus paracasei, Streptococcus thermophilus), Capsule Shell (Hydroxypropyl Methylcellulose), Vitamin C(Ascorbic Acid), Anticaking Agent (Ascorbyl Palmitate), Vitamin D2 Prep, Ferrous Fumarate, Bulking Agent (Maltodextrin), Vitamin A Prep (Vitamin A Acetate), Bioperine® Black Pepper (Piper nigrum) Extract, Copper Sulphate, Vitamin B6 (Pyridoxine Hydrochloride), Folic Acid, Sodium Selenite, Chromium Chloride, 5-Methyltetrahydrofolic Acid, Vitamin B12 (Methylcobalamin).
Suitable for vegans and vegetarians.
Gluten Free.
Food supplements should not be used as a substitute for a varied and balanced diet or a healthy lifestyle. If you are pregnant, breastfeeding, taking any medication or are under medical supervision, please consult a doctor or pharmacist before taking supplements. If you suffer any adverse reaction whilst using a supplement, discontinue use and consult your doctor. Keep out of reach of children. Allergens are highlighted in bold within the ingredients list.


Who’s it for?
Anyone over 50 who wants to look after their mental sharpness and their immune health. It works well as a daily pairing for people who've noticed changes in their focus or memory, feel like their immune system could be more resilient, or who are simply looking for optimal support for their gut-brain health with a simple daily routine.

The Healthy Ageing Blend
Most supplements in the Prime Fifty range include our Healthy Ageing Blend: important vitamins and minerals often lacking in 50+ diets, according to UK diet and nutrition data.
The blend includes vitamin D to support bones, muscles and immunity, B vitamins for energy and a healthy heart, zinc for immune and cognitive support, antioxidants to help protect cells from oxidative stress, and chromium for healthy blood sugar balance. Where possible, these important nutrients are always added, no matter which health area you’re targeting.
Together with BioPerine®, a patented black pepper extract shown to support absorption, these nutrients build a strong foundation for your health as you age.
Targeted support for brain health and mental performance
The brain is very demanding when it comes to nutrition, making up just two percent of the body but using 20 percent of our daily energy and nutrients. As we age, natural changes in both nutrition and brain structure can make it harder to satisfy those demands.
Prime Fifty’s Brain & Cognition is designed specifically for people over 50 based on how our needs change with age. Taken once a day, Brain & Cognition helps support a healthy brain and mental performance, so you can feel focused and confident.
Gut balance and immune resilience
Around 70 percent of the immune system sits in the gut. So if your digestion isn’t well supported, immunity can be affected too. As we get older, natural changes in the gut microbiome can make it harder to maintain that balance.
Prime Fifty’s Gut & Immunity supports both a healthy digestion and a robust immune system with a blend of live cultures, vitamins and minerals tailored for adults 50+, so you feel comfortable, supported and resilient every day.
"About 70 percent of our immune system is located in the gut, so maintaining a healthy microbiome becomes even more important as we get older. I designed this formulation to combine carefully selected friendly bacteria with key immune-supporting nutrients that many over-50s are lacking, to support both digestive health and everyday resilience."




Vitamin A, vitamin D, vitamin C, folic acid, vitamin B12, iron, copper and selenium all help support the normal functioning of your immune system.
The balance of the gut microbiome is very sensitive to what we eat, and an unbalanced gut flora is linked to numerous health problems. We’ve added SynBalance®, a live culture, multi-strain blend of bacteria to help re-balance your gut microbiome.
This special blend includes 14 clinically tested strains, including Lactobacillus and Bifidobacterium, to encourage a healthy, regular digestion and a diverse microbiome, with two billion colony-forming units (CFUs) in every capsule. Plus we’ve added calcium to help digestive enzymes break down and absorb nutrients from your food.
Did you know that your brain is about 60 percent fat? The fatty acid DHA (docosahexaenoic acid) is a key building block for the brain, especially grey matter, essential for mental functions like memory, emotion and movement.
The brain’s DHA needs to be continually replaced in small amounts every day, as it’s constantly being metabolised and degraded by oxidative stress. To keep up the supply, we need to obtain DHA from our diets, typically from oily fish like sardines, mackerel and salmon.
Each daily Brain & Cognition softgel provides 200mg of DHA from fish oil to help maintain a healthy brain and sharp mental focus.
Customer testimonials
Lisa H
Highly recommend these
I kept having sickness with sulphur burps have suffered for years thought I would give these a go and they have stopped the sickness and sulphur burps highly recommend these
Tom B
Clears the brain of all the fog
Works well, clears the brain of all the fog , and helps with reading and watching TV. I feel much better for taking them especially with my concentration.
Verified Customer
I have certainly noticed a difference in my energy levels and a positive change in my memory
I have recently purchased Prime Fifty Brain & Cognition and in the short term of taking the supplements I have certainly noticed a difference in my energy levels and a positive change in my memory which has given me more confidence in work and helped towards such a demanding role. A great selection of ingredients, will definitely continue taking them and re-order when needed.
FAQ
For honest help and advice, our award-winning team is here Monday to Friday from 9am to 5pm.
Freephone 0800 107 5995
From outside the UK
+44 (0) 1223 750 874
Do you ship overseas?
Yes, we ship all over the world. Shipping costs will apply.
How long until I feel a benefit?
This can vary from person to person, and also depends on the product and the benefit you're looking for. Supplements aren't pharmaceutical drugs, and they won't have an immediate effect.
Some supplements work in the background, delivering long-term health benefits without noticeable short-term differences.
But for most products, the active ingredient in your supplement needs to build up to sufficient levels in the body to begin to have an effect. In general, you should notice a benefit after 4-8 weeks of supplementation.
If you have a question about a specific product, please contact our Customer Care team for more detailed advice. hello@primefifty.com
I’m taking prescribed medication. Can I still take supplements?
If you’re taking any medication or are under medical supervision, please make sure that you consult a doctor or pharmacist before taking any supplements.
How do your subscriptions work and how do I pay for them?
Our subscriptions are designed to make life easier and ensure you never run out of your supplements.
Once subscribed, your order is automatically processed and delivered based on your chosen schedule – every 28 days.
Payments are processed automatically at the start of each subscription cycle, so you don’t need to worry about reordering manually.
You’ll receive a 3-day reminder before each shipment, and our subscriptions are fully flexible – you can amend, pause, or cancel at any time to suit your needs.
From the journal

Why Prime Fifty?
We believe ageing isn’t about limitation. It’s about supporting your body to stay capable, active, capable and independent. Prime Fifty is here to help you live the life you want to live.

What your body needs after 50 that it didn't need before
Living longer sounds good, but living well is what matters. Discover how your nutritional needs change after 50 and what the science says about maintaining strength, clarity and resilience.

Discover our Healthy Ageing Blend
As well as targeted support for your health goals, most Prime Fifty supplements also include our Healthy Ageing Blend – extra vitamins, minerals and nutrients that help to build a strong foundation for your health as you age.