




Brain & Cognition
Daily nutritional support for brain health and mental performance in adults over 50.

MENTAL FOCUS

MEMORY

BRAIN HEALTH
- Supports healthy brain function, memory and concentration
- Designed specifically for adults over 50, based on the science of ageing and UK nutrition research
- Combines omega 3 DHA with targeted vitamins, minerals and antioxidants
The brain makes up just two percent of our body weight but uses 20 percent of our daily energy and nutrients. As we age, natural changes in brain structure, metabolism and nutrient absorption can make it harder to satisfy those needs, affecting our cognitive health.
UK nutrition data also shows that many 50+ adults aren’t getting enough nutrients important for brain health, like omega 3 fatty acids, B vitamins, iron, iodine and magnesium.
Taken once a day, Brain & Cognition provides targeted nutritional support to help maintain healthy brain function and performance after 50, so you can feel focused and confident.
Helps maintain a healthy brain – with omega 3 fatty acid DHA (docosahexaenoic acid). DHA is a key building block for brain structure that needs constant replacement and replenishment from our diets.
Supports mental clarity and cognitive focus – along with DHA, each daily dose includes other key nutrients for cognitive function and mental performance that often fall short in the diets of adults 50+, including pantothenic acid (vitamin B5), iron, iodine and zinc.
Psychological and nervous system support – B vitamins, magnesium and L-methyl folate support the nervous system and normal psychological function, playing a role in mood, mental wellbeing, and coordinating bodily movement and sensation.
Protects brain cells from daily damage – with antioxidants such as vitamin E and selenium, along with polyphenols from green tea and grape seed, to help protect brain cells from damage caused by oxidative stress, which increases as we age.
Includes our Healthy Ageing Blend – a blend of vitamins and minerals often lacking in 50+ diets but important for general health as we age, including muscle function, heart health, blood sugar balance, immune resilience and cellular protection.
Supports nutrient absorption – with easy-to-absorb mineral forms, plus Bioperine®, a patented black pepper extract shown to increase the absorption of vitamins and minerals, which can become harder for the older gut.
Take one capsule and one softgel daily, preferably together, with a cold drink at mealtimes.
28 capsules and 28 softgels, 28-day supply
| Ingredient | Per capsule | % NRV* |
|---|---|---|
| Vitamin D3 | 20µg (800 IU) | 400% |
| Vitamin E | 26mg (ɑ-TE)# | 217% |
| Vitamin C | 80mg | 100% |
| Vitamin B1 (Thiamin) | 5mg | 455% |
| Vitamin B2 (Riboflavin) | 4.2mg | 300% |
| Vitamin B3 (Niacin) | 16mg (NE)# | 100% |
| Vitamin B6 | 10mg | 571% |
| Folic Acid | 200µg | 100% |
| Folate | 50µg | 25% |
| Vitamin B12 | 25µg | 1000% |
| Pantothenic Acid (vitamin B5) | 21mg | 350% |
| Magnesium | 60mg | 16% |
| Iron | 7mg | 50% |
| Zinc | 15mg | 150% |
| Copper | 1mg | 100% |
| Manganese | 2mg | 100% |
| Selenium | 110µg | 200% |
| Chromium | 40µg | 100% |
| Iodine | 150µg | 100 |
| Carnitine | 10mg | N/A |
| N-Acetyl L-Cysteine | 10mg | N/A |
| Grape Seed Extract | 25mg | N/A |
| Green Tea Extract 4:1 | 20mg | N/A |
| Co-Enzyme Q10 | 10mg | N/A |
| BioPerine® Black Pepper Extract |
3mg | N/A |
| Ingredient | Per softgel | % NRV* |
|---|---|---|
| Fish Oil of which Omega 3 including EPA including DHA |
500mg 300mg 30mg 200mg |
N/A |
| Vitamin E | 6mg (α-TE)# | 50% |
* Nutrient Reference Value #a-TE: alpha-Tocopherol Equivalent; NE: Niacin Equivalent
CAPSULE: Magnesium Oxide, Capsule Shell (Hydroxypropyl Methylcellulose), Vitamin C (Ascorbic Acid), Vitamin E (D-Alpha Tocopherol Acid Succinate), Pantothenic Acid (Calcium Pantothenate), Grape Seed (Vitis vinifera) Extract (Maltodextrin), Green Tea (Camellia sinensis) Extract, Zinc Oxide, Ferrous Fumarate, Vitamin B3 (Nicotinamide), N-Acetyl L-Carnitine Hydrochloride, Anticaking Agents (Tricalcium Phosphate, Magnesium Stearate), Vitamin B6 (Pyridoxine Hydrochloride), Vitamin D3 Prep (Cholecalciferol), Co-Enzyme Q10, N-Acetyl L-Cysteine, Thiamin (Thiamin Hydrochloride), Ferrous Citrate, Riboflavin, Manganese Citrate, Manganese Sulphate, BioPerine® Black Pepper (Piper nigrum) Extract, Copper Sulphate, Copper Citrate, Folic Acid, Sodium Selenite, Chromium Chloride, Potassium Iodide, 5-Methyltetrahydrofolic Acid, Vitamin B12 (Methylcobalamin).
SOFTGEL: Fish Oil, Capsule Shell (Bovine Gelatin, Glycerol), vitamin E (DL-a- Tocopheryl Acetate).
Food supplements should not be used as a substitute for a varied and balanced diet or a healthy lifestyle. If you are pregnant, breastfeeding, taking any medication or are under medical supervision, please consult a doctor or pharmacist before taking supplements. If you suffer any adverse reaction whilst using a supplement, discontinue use and consult your doctor. Keep out of reach of children. Allergens are highlighted in bold within the ingredients list.


Who’s it for?
Brain & Cognition is for anyone over 50 looking to secure their brain health, mental clarity, focus and cognitive performance as they get older.

The Healthy Ageing Blend
Most supplements in the Prime Fifty range include our Healthy Ageing Blend: important vitamins and minerals often lacking in 50+ diets, according to UK diet and nutrition data.
The blend includes vitamin D to support bones, muscles and immunity, B vitamins for energy and a healthy heart, zinc for immune and cognitive support, antioxidants to help protect cells from oxidative stress, and chromium for healthy blood sugar balance. Where possible, these important nutrients are always added, no matter which health area you’re targeting.
Together with BioPerine®, a patented black pepper extract shown to support absorption, these nutrients build a strong foundation for your health as you age.
"The brain accounts for around two percent of our body weight, but uses roughly 20 percent of our energy and nutrients. As we get a bit older, maintaining optimal levels of key nutrients like DHA, B vitamins and antioxidants becomes more important for supporting cognitive function and long-term brain health."



Did you know that your brain is about 60 percent fat? The fatty acid DHA (docosahexaenoic acid) is a key building block for the brain, especially grey matter, essential for mental functions like memory, emotion and movement.
The brain’s DHA needs to be continually replaced in small amounts every day, as it’s constantly being metabolised and degraded by oxidative stress. To keep up the supply, we need to obtain DHA from our diets, typically from oily fish like sardines, mackerel and salmon.
Each daily Brain & Cognition softgel provides 200mg of DHA from fish oil to help maintain a healthy brain and sharp mental focus.
Nutrition isn't just about what you put into your body, it’s about what your body can actually use. Breaking down and absorbing nutrients from what we eat becomes harder as we age, caused by reduced stomach acid and other factors. That can affect how well we extract vitamins and minerals from both food and supplements.
That’s why we include BioPerine®, a patented extract of piperine from black pepper shown by multiple studies to enhance the bioavailability of a wide range of vitamins, minerals and other nutrients, helping your body put them to use.
Customer testimonials
Tom B
Clears the brain of all the fog
Works well, clears the brain of all the fog , and helps with reading and watching TV. I feel much better for taking them especially with my concentration
Verified Customer
I have certainly noticed a difference in my energy levels and a positive change in my memory
I have recently purchased Prime Fifty Brain & Cognition and in the short term of taking the supplements I have certainly noticed a difference in my energy levels and a positive change in my memory which has given me more confidence in work and helped towards such a demanding role. A great selection of ingredients, will definitely continue taking them and re-order when needed.
Janet U
No more fuzzy brain fog!
This supplement has given me back my confidence at work. No more fuzzy brain fog! Thank you, the tablets are easy to take and guess what I actually remember to take them!
FAQ
For honest help and advice, our award-winning team is here Monday to Friday from 9am to 5pm.
Freephone 0800 107 5995
From outside the UK
+44 (0) 1223 750 874
Do you ship overseas?
Yes, we ship all over the world. Shipping costs will apply.
How long until I feel a benefit?
This can vary from person to person, and also depends on the product and the benefit you're looking for. Supplements aren't pharmaceutical drugs, and they won't have an immediate effect.
Some supplements work in the background, delivering long-term health benefits without noticeable short-term differences.
But for most products, the active ingredient in your supplement needs to build up to sufficient levels in the body to begin to have an effect. In general, you should notice a benefit after 4-8 weeks of supplementation.
If you have a question about a specific product, please contact our Customer Care team for more detailed advice. hello@primefifty.com
I’m taking prescribed medication. Can I still take supplements?
If you’re taking any medication or are under medical supervision, please make sure that you consult a doctor or pharmacist before taking any supplements.
How do your subscriptions work and how do I pay for them?
Our subscriptions are designed to make life easier and ensure you never run out of your supplements.
Once subscribed, your order is automatically processed and delivered based on your chosen schedule – every 28 days.
Payments are processed automatically at the start of each subscription cycle, so you don’t need to worry about reordering manually.
You’ll receive a 3-day reminder before each shipment, and our subscriptions are fully flexible – you can amend, pause, or cancel at any time to suit your needs.
From the journal

Why Prime Fifty?
We believe ageing isn’t about limitation. It’s about supporting your body to stay capable, active, capable and independent. Prime Fifty is here to help you live the life you want to live.

What your body needs after 50 that it didn't need before
Living longer sounds good, but living well is what matters. Discover how your nutritional needs change after 50 and what the science says about maintaining strength, clarity and resilience.

Discover our Healthy Ageing Blend
As well as targeted support for your health goals, most Prime Fifty supplements also include our Healthy Ageing Blend – extra vitamins, minerals and nutrients that help to build a strong foundation for your health as you age.