





Gut & Immunity
Daily nutritional support for gut and immune health with live cultures, vitamins and minerals.

GUT BALANCE

IMMUNE SUPPORT

EVERYDAY RESILIANCE
- Supports digestion and immune health
- 14 live bacterial cultures important for a healthy, balanced microbiome
- Immunity-supporting vitamins and minerals often lacking in UK diets after 50
Around 70% of your immune system is in your gut, which makes gut health central to your immune resilience. As we age, natural changes in the gut microbiome called dysbiosis can upset the balance of beneficial bacteria.
At the same time, UK nutrition data shows that many adults over 50 fall short of key vitamins and minerals that support immune function. Maintaining a healthy gut helps support digestion and everyday immune resilience.
Gut & Immunity supports both a healthy digestion and a resilient immune system with a blend of live cultures, vitamins and minerals tailored for adults 50+.
Strengthens your body’s natural defences – About 70 percent of your immune system is in your gut. Gut & Immunity supports it with a blend of friendly live bacteria and immune-supporting nutrients often missing from 50+ diets – including iron, vitamins D and C and selenium.
Restores a balanced gut microbiome for healthy digestion – with 14 strains of live bacterial cultures including Lactobacillus and Bifidobacterium, to encourage a healthy, regular digestion and a diverse microbiome. Two billion colony-forming units (CFUs) in every capsule.
Includes our Healthy Ageing Blend – a blend of vitamins and minerals often lacking in 50+ diets but important for general health as we age, including muscle function, heart health, blood sugar balance, immune resilience and cellular protection.
Supports nutrient absorption – with easy-to-absorb mineral forms, plus Bioperine®, a patented black pepper extract shown to increase the absorption of vitamins and minerals, which can become harder for the older gut.
Take one capsule per day with a cold drink at meal times.
| Ingredient | Per tablet | % NRV* |
|---|---|---|
| Vitamin A | 400µg (RE) | 50% |
| Vitamin D2 | 20µg (800IU) | 400% |
| Vitamin C | 40mg | 50% |
| Vitamin B6 | 1.4mg | 100% |
| Folic Acid | 200µg | 100% |
| Folate | 50µg | 25% |
| Vitamin B12 | 25µg | 1000% |
| Calcium | 120mg | 15% |
| Iron | 3mg | 21% |
| Copper | 1mg | 100% |
| Selenium | 110µg | 200% |
| Chromium | 30µg | 75% |
| BioPerine® Black Pepper Extract | 3mg | N/A |
| Synbalance® Multi Strain live Bacteria Blend | 2 Billion (2 x 109 CFU) | N/A |
* Nutrient Reference Value
Manufactured in a GMP (Good Manufacturing Practice) facility in the UK
Calcium Carbonate, SynBalance® Multi Strain Live Culture Blend (Bifidobacterium lactis, Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus acidophilus, Bifidobacterium breve, Lactobacillus casei, Bifidobacterium bifidum, Bifidobacterium infantis, Bifidobacterium longum, Lactobacillus bulgaricus, Lactobacillus reuteri, Lactobacillus salivarius, Lactobacillus paracasei, Streptococcus thermophilus), Capsule Shell (Hydroxypropyl Methylcellulose), Vitamin C(Ascorbic Acid), Anticaking Agent (Ascorbyl Palmitate), Vitamin D2 Prep, Ferrous Fumarate, Bulking Agent (Maltodextrin), Vitamin A Prep (Vitamin A Acetate), Bioperine® Black Pepper (Piper nigrum) Extract, Copper Sulphate, Vitamin B6 (Pyridoxine Hydrochloride), Folic Acid, Sodium Selenite, Chromium Chloride, 5-Methyltetrahydrofolic Acid, Vitamin B12 (Methylcobalamin).
Suitable for vegans and vegetarians.
Gluten Free.
Food supplements should not be used as a substitute for a varied and balanced diet or a healthy lifestyle. If you are pregnant, breastfeeding, taking any medication or are under medical supervision, please consult a doctor or pharmacist before taking supplements. If you suffer any adverse reaction whilst using a supplement, discontinue use and consult your doctor. Keep out of reach of children. Allergens are highlighted in bold within the ingredients list.


Who’s it for?
Gut & Immunity is suitable for all adults aged 50+ who want to support healthy digestion and strengthen their everyday immune resilience.
If you’ve recently taken antibiotics, it can help to restore your gut microbiome balance. It can also help if you experience digestive discomfort from time to time, or feel your immune health is under pressure due to stress, disrupted sleep or a busy routine.

The Healthy Ageing Blend
Most supplements in the Prime Fifty range include our Healthy Ageing Blend: important vitamins and minerals often lacking in 50+ diets, according to UK diet and nutrition data.
The blend includes vitamin D to support bones, muscles and immunity, B vitamins for energy and a healthy heart, zinc for immune and cognitive support, antioxidants to help protect cells from oxidative stress, and chromium for healthy blood sugar balance. Where possible, these important nutrients are always added, no matter which health area you’re targeting.
Together with BioPerine®, a patented black pepper extract shown to support absorption, these nutrients build a strong foundation for your health as you age.
"About 70 percent of our immune system is located in the gut, so maintaining a healthy microbiome becomes even more important as we get older. I designed this formulation to combine carefully selected friendly bacteria with key immune-supporting nutrients that many over-50s are lacking, to support both digestive health and everyday resilience."




The balance of the gut microbiome is very sensitive to what we eat, and an unbalanced gut flora is linked to numerous health problems. We’ve added SynBalance®, a live culture, multi-strain blend of bacteria to help re-balance your gut microbiome.
This special blend includes 14 clinically tested strains, including Lactobacillus and Bifidobacterium, to encourage a healthy, regular digestion and a diverse microbiome, with two billion colony-forming units (CFUs) in every capsule. Plus we’ve added calcium to help digestive enzymes break down and absorb nutrients from your food.
Ingredient highlights
Vitamin A, vitamin D, vitamin C, folic acid, vitamin B12, iron, copper and selenium all help support the normal functioning of your immune system.
Ingredient highlights
Nutrition isn't just about what you put into your body, it’s about what your body can actually use. Breaking down and absorbing nutrients from what we eat becomes harder as we age, caused by reduced stomach acid and other factors. That can affect how well we extract vitamins and minerals from both food and supplements.
That’s why we include BioPerine®, a patented extract of piperine from black pepper shown by multiple studies to enhance the bioavailability of a wide range of vitamins, minerals and other nutrients, helping your body put them to use.
Customer testimonials
Lisa H
Highly recommend these
I kept having sickness with sulphur burps have suffered for years thought I would give these a go and they have stopped the sickness and sulphur burps highly recommend these
DIANE S
Keep my gut nice and healthy
They are good they keep my gut nice and healthy
Wj Mutter
I'll keep taking them, they're a keeper
Prime Fifty - Gut & Immunity. Great product, been taking it for more than 3 years. Over all I feel improved and most importantly I recently caught a cold/flu and was happy to discover I didn't experience a heavy bout. Also, I fully recovered within the week. I'll keep taking them, they're a keeper!
FAQ
For honest help and advice, our award-winning team is here Monday to Friday from 9am to 5pm.
Freephone 0800 107 5995
From outside the UK
+44 (0) 1223 750 874
Do you ship overseas?
Yes, we ship all over the world. Shipping costs will apply.
How long until I feel a benefit?
This can vary from person to person, and also depends on the product and the benefit you're looking for. Supplements aren't pharmaceutical drugs, and they won't have an immediate effect.
Some supplements work in the background, delivering long-term health benefits without noticeable short-term differences.
But for most products, the active ingredient in your supplement needs to build up to sufficient levels in the body to begin to have an effect. In general, you should notice a benefit after 4-8 weeks of supplementation.
If you have a question about a specific product, please contact our Customer Care team for more detailed advice. hello@primefifty.com
I’m taking prescribed medication. Can I still take supplements?
If you’re taking any medication or are under medical supervision, please make sure that you consult a doctor or pharmacist before taking any supplements.
How do your subscriptions work and how do I pay for them?
Our subscriptions are designed to make life easier and ensure you never run out of your supplements.
Once subscribed, your order is automatically processed and delivered based on your chosen schedule – every 28 days.
Payments are processed automatically at the start of each subscription cycle, so you don’t need to worry about reordering manually.
You’ll receive a 3-day reminder before each shipment, and our subscriptions are fully flexible – you can amend, pause, or cancel at any time to suit your needs.
From the journal

Why Prime Fifty?
We believe ageing isn’t about limitation. It’s about supporting your body to stay capable, active, capable and independent. Prime Fifty is here to help you live the life you want to live.

What your body needs after 50 that it didn't need before
Living longer sounds good, but living well is what matters. Discover how your nutritional needs change after 50 and what the science says about maintaining strength, clarity and resilience.

Discover our Healthy Ageing Blend
As well as targeted support for your health goals, most Prime Fifty supplements also include our Healthy Ageing Blend – extra vitamins, minerals and nutrients that help to build a strong foundation for your health as you age.