






Fighting Fatigue
Daily energy multi-nutrient with B vitamins, minerals and co-enzyme Q10.

ENERGISED

CAPABLE

ACTIVE
- Supports daily energy and stamina, reduces tiredness and fatigue
- Targeted for people aged 50+, based on research into UK diets and the science of ageing
- Includes co-enzyme Q10 and key minerals to support energy and muscle function
Daily energy keeps us active and able to keep doing the things we love. But in a Prime Fifty survey of 1,000 adults aged 50+, low energy levels was one of the most frequently reported challenges.
UK diet and nutrition survey data helps explain why. Many adults over 50 fall short of daily recommended targets for key energy-supporting nutrients, including B vitamins, folate, iron, magnesium and co-enzyme Q10. Targeted nutritional support can help sustain steady energy and everyday vitality.
Fighting Fatigue helps you stay energised and active with easy-to-absorb vitamins and minerals that support daily energy – all in a single daily tablet.
Designed for people over 50, Fighting Fatigue is based on research into UK diets and how our nutritional needs change with age.
Daily energy nutrients targeted for 50+ – Dietary surveys show that most adults 50+ don’t meet the recommended daily targets of vitamins B1, B2, B3, B12 and B6, folate, iron, magnesium and zinc – key nutrients that support energy levels throughout the day.
Supports cellular energy for everyday stamina – with co-enzyme Q10 (or ubiquinone), an antioxidant that helps produce energy in our cells to fuel muscles and organs day to day. Natural production of co-enzyme Q10 declines with age, and can be affected by statin use.
Supports nutrient absorption in the older gut – with easy-to-absorb mineral forms plus Bioperine®, a patented black pepper extract shown to increase the absorption of vitamins and minerals.
Includes our Healthy Ageing Blend – a blend of vitamins and minerals often lacking in 50+ diets but important for general health as we age, including muscle function, heart health, blood sugar balance, immune resilience and cellular protection.
Take one tablet a day with a cold drink at mealtimes.
| Ingredient | Per tablet | % NRV* |
|---|---|---|
| Vitamin D3 | 20µg (800 IU) | 400% |
| Vitamin E | 12mg (ɑ-TE)# | 100% |
| Vitamin C | 160mg | 200% |
| Vitamin B1 (Thiamin) | 2.2mg | 200% |
| Vitamin B2 (Riboflavin) | 4.2mg | 300% |
| Vitamin B3 (Niacin) | 36mg (NE)# | 225% |
| Vitamin B6 (pyridoxine) | 5mg | 357% |
| Folic acid | 200µg | 100% |
| Vitamin B12 | 25µg | 1,000% |
| Biotin | 50µg | 100% |
| Pantothenic Acid (Vitamin B5) | 6mg | 100% |
| Calcium | 254mg | 32% |
| Magnesium | 60mg | 16% |
| Iron | 3mg | 21% |
| Zinc | 7mg | 70% |
| Selenium | 70µg | 127% |
| Chromium | 30µg | 75% |
| Iodine | 100µg | 67% |
| BioPerine® Black Pepper Extract |
3mg | N/A |
| Co-Enzyme Q10 | 5mg | N/A |
| Grape Seed Extract | 25mg | N/A |
* Nutrient Reference Value #a-TE: alpha-Tocopherol Equivalent; NE: Niacin Equivalent
Calcium Carbonate Prep (Maltodextrin), Vitamin C Prep (Ascorbic Acid, Hydroxypropyl Methylcellulose), Bulking Agent (Cellulose), Magnesium Oxide, Magnesium Citrate, Coating (Polydextrose, Hydroxypropyl Methylcellulose, Calcium Carbonate, Medium-Chain Triglycerides, Yellow Iron Oxide, Copper Chlorophyllin), Nicotinamide, Vitamin E Prep (DL-a-Tocopherol Acetate), Vitamin D3 Prep (Cholecalciferol), Anticaking Agent (Magnesium Stearate), Ferrous Fumarate, Pantothenic Acid (Calcium Pantothenate), Zinc Oxide, Vitamin B6 (Pyridoxine Hydrochloride), Co-Enzyme Q10, Riboflavin, Zinc Citrate, Thiamin (Thiamin Hydrochloride), Ferrous Citrate, BioPerine® Black Pepper (Piper nigrum) Extract, Chromium Picolinate, Grape (Vitis vinifera) Seed Extract (Maltodextrin), Sodium Selenate, Folic Acid (L-5-Methyltetrahydrofolate Calcium), Potassium Iodide, Biotin, Vitamin B12 (Methylcobalamin).
Suitable for vegetarians.
Food supplements should not be used as a substitute for a varied and balanced diet or a healthy lifestyle. If you are pregnant, breastfeeding, taking any medication or are under medical supervision, please consult a doctor or pharmacist before taking supplements. If you suffer any adverse reaction whilst using a supplement, discontinue use and consult your doctor. Keep out of reach of children. Allergens are highlighted in bold within the ingredients list.

key nutrients for energy
UK diet surveys show that many people over 50 fall short on key nutrients for energy, while the body's natural energy systems change with age. When that happens, tiredness can creep in and make even familiar routines start to feel harder.
Fighting Fatigue is a daily energy multivitamin designed specifically for people over 50. It’s formulated to help support everyday energy and reduce tiredness and fatigue, so you feel more capable and ready for your day.

Who’s it for?
Fighting Fatigue is for anyone 50+ looking to maintain their energy and stamina throughout the day. It can help if you're going through a busy or stressful period that has left you feeling low in energy, or if you’re finding it harder than usual to keep up with your everyday routine.

The Healthy Ageing Blend
Most supplements in the Prime Fifty range include our Healthy Ageing Blend: important vitamins and minerals often lacking in 50+ diets, according to UK diet and nutrition data.
The blend includes vitamin D to support bones, muscles and immunity, B vitamins for energy and a healthy heart, zinc for immune and cognitive support, antioxidants to help protect cells from oxidative stress, and chromium for healthy blood sugar balance. Where possible, these important nutrients are always added, no matter which health area you’re targeting.
Together with BioPerine®, a patented black pepper extract shown to support absorption, these nutrients build a strong foundation for your health as you age.
"When I looked at the UK diet and nutrition data, it was clear that many people over 50 simply aren’t getting enough of the key nutrients involved in energy production. Fighting Fatigue is designed to correct those gaps – supporting energy at a cellular level so you can stay active and capable day to day."




Otherwise known as thiamin, riboflavin and niacin, these B vitamins play a key role in our energy metabolism, helping to reduce tiredness and maintain energy levels. Riboflavin also helps the body metabolise iron, a key process for making energy.
Also known as ubiquinone, Co-enzyme Q10 is a natural antioxidant that helps produce energy that our cells need to fuel muscles and organs day to day. Our bodies become less efficient at making ubiquinone as we get older, and it can be affected by statins.
Nutrition isn't just about what you put into your body, it’s about what your body can actually use. Breaking down and absorbing nutrients from what we eat becomes harder as we age, caused by reduced stomach acid and other factors. That can affect how well we extract vitamins and minerals from both food and supplements.
That’s why we include BioPerine®, a patented extract of piperine from black pepper shown by multiple studies to enhance the bioavailability of a wide range of vitamins, minerals and other nutrients, helping your body put them to use.
Customer testimonials
Catharine B
Have noticed a significant difference in my energy levels
I have been taking Fighting Fatigue for just over two weeks and in the last few days have noticed a significant difference in my energy levels. I have felt tired for years so am amazed by the result.
James M
Highly recommended this product
More energy and highly recommended this product I have been taking for almost three years when I first seen them on the QVC shopping tv. While I had been another supplement and it was good I though I would try Prime Fifty and I felt a bit more lively with these. The delivery was very good considering the time we are in. Cheers
Carole B
They certainly make a difference
I bought these for my 90 year old mother about 2 years ago and she advises me that they certainly make a difference making her feel much better and more active. She doesn't want to be without them so they must be good.
FAQ
For honest help and advice, our award-winning team is here Monday to Friday from 9am to 5pm.
Freephone 0800 107 5995
From outside the UK
+44 (0) 1223 750 874
Do you ship overseas?
Yes, we ship all over the world. Shipping costs will apply.
How long until I feel a benefit?
This can vary from person to person, and also depends on the product and the benefit you're looking for. Supplements aren't pharmaceutical drugs, and they won't have an immediate effect.
Some supplements work in the background, delivering long-term health benefits without noticeable short-term differences.
But for most products, the active ingredient in your supplement needs to build up to sufficient levels in the body to begin to have an effect. In general, you should notice a benefit after 4-8 weeks of supplementation.
If you have a question about a specific product, please contact our Customer Care team for more detailed advice. hello@primefifty.com
I’m taking prescribed medication. Can I still take supplements?
If you’re taking any medication or are under medical supervision, please make sure that you consult a doctor or pharmacist before taking any supplements.
How do your subscriptions work and how do I pay for them?
Our subscriptions are designed to make life easier and ensure you never run out of your supplements.
Once subscribed, your order is automatically processed and delivered based on your chosen schedule – every 28 days.
Payments are processed automatically at the start of each subscription cycle, so you don’t need to worry about reordering manually.
You’ll receive a 3-day reminder before each shipment, and our subscriptions are fully flexible – you can amend, pause, or cancel at any time to suit your needs.
From the journal

Why Prime Fifty?
We believe ageing isn’t about limitation. It’s about supporting your body to stay capable, active, capable and independent. Prime Fifty is here to help you live the life you want to live.

What your body needs after 50 that it didn't need before
Living longer sounds good, but living well is what matters. Discover how your nutritional needs change after 50 and what the science says about maintaining strength, clarity and resilience.

Discover our Healthy Ageing Blend
As well as targeted support for your health goals, most Prime Fifty supplements also include our Healthy Ageing Blend – extra vitamins, minerals and nutrients that help to build a strong foundation for your health as you age.