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ENERGISED & ACTIVE

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Support for the energy to stay active and the joints and bones to do it comfortably — two formulas built around what the body actually needs after 50.

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ENERGISED

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Why it matters after 50

Fighting Fatigue to maintain daily energy and stamina — with co-enzyme Q10, a full B vitamin complex and key minerals to support energy at a cellular level
Healthy Joints & Bones for joint flexibility, bone strength and connective tissue support — with glucosamine, chondroitin, vitamins D and K and much more
Both designed specifically for adults over 50, based on UK nutrition research and the science of ageing

Staying active as you get older isn't just about willpower. It depends on two things working in tandem: having the energy to keep moving, and having joints and bones that can take it. When either starts to struggle, the other tends to suffer too — fatigue makes it harder to exercise, and discomfort makes it harder to want to.

After 50, both come under pressure at the same time. UK diet surveys consistently show that adults in this age group fall short on the nutrients that drive cellular energy production — B vitamins, iron, magnesium, co-enzyme Q10. Meanwhile, joint cartilage faces more wear and tear, bone density gradually declines, and the connective tissues holding it all together rely on nutrients that are equally hard to get enough of from diet alone.

This bundle tackles both sides of that equation together.

How it works

Fighting Fatigue

Low energy was one of the most commonly reported challenges when Prime Fifty surveyed 1,000 adults over 50 — and UK nutritional data gives a pretty clear reason why. Most people in this age group aren't hitting their daily recommended targets for vitamins B1, B2, B3, B6, B12 and folate, or for iron, magnesium and zinc — all nutrients that play a direct role in how the body produces and sustains energy.

Fighting Fatigue addresses those gaps in a single daily tablet. The full B vitamin complex covers the energy metabolism side — thiamin, riboflavin and niacin in particular help the body convert food into usable energy, while B12 and folate support the nervous system and help reduce tiredness. Iron and magnesium contribute to normal energy-yielding metabolism, with magnesium also supporting muscle function — important for anyone who wants to stay physically active.

Co-enzyme Q10 is worth singling out. It's a natural antioxidant that plays a central role in cellular energy production, fuelling muscles and organs at a fundamental level. The body becomes less efficient at making it as we age, and statin use — common in this age group — can reduce levels further. BioPerine® is included throughout to support absorption, since even well-formulated supplements are only as useful as what the gut can actually take up.

Healthy Joints & Bones

Joints need more than one nutrient to stay healthy, and this formula reflects that. Glucosamine and chondroitin — both found naturally in joint cartilage — are the headline ingredients, helping maintain its elasticity and structure. Hydrolysed collagen, MSM and hyaluronic acid support the connective tissues around the joints, including tendons and ligaments, while copper and manganese contribute to their normal maintenance.

For bones, calcium, zinc and vitamins D and K work as a team. It's not enough to just provide calcium — vitamin K directs it from the bloodstream into the bones where it's actually needed, and vitamin D supports absorption as well as helping reduce the risk of falls in the over-60s, where falling is a significant risk factor for fractures. Calcium and vitamin D together have also been shown to help reduce bone mineral loss in postmenopausal women.

Rounding things out, selenium, zinc and vitamin C help protect joint tissues from oxidative stress — which tends to increase with age and can quietly accelerate cartilage degradation over time. BioPerine® again supports absorption throughout.

How to take

Fighting Fatigue — one tablet a day with a cold drink at mealtimes. 28 tablets per pack, 28-day supply. Suitable for vegetarians.

Healthy Joints & Bones — two tablets a day with a cold drink at mealtimes. 56 tablets per pack, 28-day supply. Gluten-free and lactose-free.

If you're on anti-coagulant medication (blood thinners), please speak to your doctor before taking Healthy Joints & Bones. If they're happy for you to use it, take one tablet per day rather than the full two-tablet dose.

Ingredients & nutritional information

Healthy Joints and Bones:

Ingredient	Per two tablets	%NRV*
Vitamin D3	20µg (800IU)	400%
Vitamin E	12mg (ɑ-TE)#	100%
Vitamin K (K1 + K2)	150µg	200%
Vitamin C	160mg	200%
Riboflavin (Vitamin B2)	4.2mg	300%
Vitamin B6	5mg	357%
Folic Acid (as Folate)	200µg	100%
Vitamin B12	25µg	1000%
Calcium	195mg	24%
Zinc	7mg	70%
Copper	1mg	100%
Manganese	1mg	50%
Selenium	71µg	129
Chromium	30µg	75%
Glucosamine Sulphate 2KCl providing Glucosamine	1000mg 592mg	N/A
Chondroitin Sulphate	250mg	N/A
Hydrolysed Collagen	100mg	N/A
MSM	50mg	N/A
Hyaluronic Acid	5mg
Grape Seed Extract (Equiv to)	25mg	N/A
BioPerine®	3mg	N/A

* Nutrient Reference Value #ɑ-TE: alpha-Tocopherol Equivalent

IU: International Units

If you are taking anti-coagulants (blood thinners) do not take this product except on the advice of a doctor. You should only take 1 tablet instead of the full dose.

Glucosamine Sulphate 2KCl Prep (Polyvinylpyrrolidone) (Crustaceans), Calcium Carbonate Prep (Maltodextrin), Chondroitin Sulphate Sodium (Fish), Vitamin C Prep (Ascorbic Acid, Hydroxypropyl Methylcellulose), Hydrolysed Marine Collagen (Fish), Coating (Calcium Carbonate, Hydroxypropyl Methylcellulose, Isomalt, Medium Chain Triglycerides), Bulking Agent (Cellulose), MSM (Methylsulphonyl Methane), Vitamin E Prep (DL-ɑ-Tocopherol Acetate, Silicon Dioxide), Anticaking Agent (Magnesium Stearate), Vitamin D3 Prep (Cholecalciferol), Zinc Oxide, Pyridoxine Hydrochloride, Hyaluronic Acid, Riboflavin, Zinc Citrate, BioPerine® Black Pepper (Piper nigrum) Extract, Manganese Sulphate, Copper Sulphate, Vitamin K1 Prep (Maltodextrin), Vitamin K2 Prep (Microcrystalline Cellulose), Manganese Citrate, Copper Citrate,L-5-Methyltetrahydrofolate Calcium, Chromium Picolinate, Grape (Vitis vinifera) Seed Extract, Sodium Selenate, Methylcobalamin.

If you are taking anti-coagulants (blood thinners) do not take this product except on the advice of a doctor. You should only take 1 tablet instead of the full dose.

Fighting Fatigue:

Ingredient	Per tablet	% NRV*
Vitamin D3	20µg (800 IU)	400%
Vitamin E	12mg (ɑ-TE)^#	100%
Vitamin C	160mg	200%
Vitamin B1 (Thiamin)	2.2mg	200%
Vitamin B2 (Riboflavin)	4.2mg	300%
Vitamin B3 (Niacin)	36mg (NE)^#	225%
Vitamin B6 (pyridoxine)	5mg	357%
Folic acid (as folate)	100µg	50%
Vitamin B12	25µg	1,000%
Biotin	50µg	100%
Pantothenic Acid (Vitamin B5)	6mg	100%
Calcium	254mg	32%
Magnesium	60mg	16%
Iron	3mg	21%
Zinc	7mg	70%
Selenium	70µg	127%
Chromium	30µg	75%
Iodine	100µg	67%
BioPerine^® Black Pepper Extract	3mg	N/A
Co-Enzyme Q10	5mg	N/A
Grape Seed Extract	25mg	N/A

* Nutrient Reference Value #a-TE: alpha-Tocopherol Equivalent; NE: Niacin Equivalent

Calcium Carbonate Prep (Maltodextrin), Vitamin C Prep (Ascorbic Acid, Hydroxypropyl Methylcellulose), Bulking Agent (Cellulose), Magnesium Oxide, Magnesium Citrate, Coating (Polydextrose, Hydroxypropyl Methylcellulose, Calcium Carbonate, Medium-Chain Triglycerides, Yellow Iron Oxide, Copper Chlorophyllin), Nicotinamide, Vitamin E Prep (DL-a-Tocopherol Acetate), Vitamin D3 Prep (Cholecalciferol), Anticaking Agent (Magnesium Stearate), Ferrous Fumarate, Pantothenic Acid (Calcium Pantothenate), Zinc Oxide, Vitamin B6 (Pyridoxine Hydrochloride), Co-Enzyme Q10, Riboflavin, Zinc Citrate, Thiamin (Thiamin Hydrochloride), Ferrous Citrate, BioPerine® Black Pepper (Piper nigrum) Extract, Chromium Picolinate, Grape (Vitis vinifera) Seed Extract (Maltodextrin), Sodium Selenate, Folic Acid (L-5-Methyltetrahydrofolate Calcium), Potassium Iodide, Biotin, Vitamin B12 (Methylcobalamin).

Suitable for vegetarians.

Food supplements should not be used as a substitute for a varied and balanced diet or a healthy lifestyle. If you are pregnant, breastfeeding, taking any medication or are under medical supervision, please consult a doctor or pharmacist before taking supplements. If you suffer any adverse reaction whilst using a supplement, discontinue use and consult your doctor. Keep out of reach of children. Allergens are highlighted in bold within the ingredients list.

ENERGISED & ACTIVE

Who’s it for?

Anyone over 50 who wants to stay active — and wants the energy and the physical foundation to actually do it. It's a natural pairing for people who've noticed their get-up-and-go isn't quite what it was, or who find that joint discomfort is starting to get in the way of doing the things they enjoy. Taken together, the two tablets from Fighting Fatigue and Healthy Joints & Bones make for a straightforward daily routine that covers a lot of ground.

The Healthy Ageing Blend

Most supplements in the Prime Fifty range include our Healthy Ageing Blend: important vitamins and minerals often lacking in 50+ diets, according to UK diet and nutrition data.

The blend includes vitamin D to support bones, muscles and immunity, B vitamins for energy and a healthy heart, zinc for immune and cognitive support, antioxidants to help protect cells from oxidative stress, and chromium for healthy blood sugar balance. Where possible, these important nutrients are always added, no matter which health area you’re targeting.

Together with BioPerine®, a patented black pepper extract shown to support absorption, these nutrients build a strong foundation for your health as you age.

Learn more

Movement, strength and stability

Staying mobile as we get older depends on healthy joints that move smoothly and strong bones for stability and support. As we age, natural changes and wear and tear make nutrition all the more important for maintaining them.

Prime Fifty’s Healthy Joints & Bones is designed specifically for the over 50s with comprehensive support for joints, bones and connective tissue, helping to maintain movement, strength and stability.

Stay energised and active

Low daily energy levels are one of the most frequently reported challenges for people over 50. UK diet and nutrition survey data helps explain why: too many of us are missing our recommended daily targets for key energy-supporting nutrients.

Fighting Fatigue helps you stay energised and active with easy-to-absorb vitamins and minerals that support daily energy – all in a single daily tablet.

"When I looked at the UK diet and nutrition data, it was clear that many people over 50 simply aren’t getting enough of the key nutrients involved in energy production. Fighting Fatigue is designed to correct those gaps – supporting energy at a cellular level so you can stay active and capable day to day."

Dr. Max Gowland, PhD

Co-enzyme Q10 for everyday stamina

Also known as ubiquinone, Co-enzyme Q10 is a natural antioxidant that helps produce energy that our cells need to fuel muscles and organs day to day. Our bodies become less efficient at making ubiquinone as we get older, and it can be affected by statins.

Vitamins B1, B2 & B3 for daily energy

Otherwise known as thiamin, riboflavin and niacin, these B vitamins play a key role in our energy metabolism, helping to reduce tiredness and maintain energy levels. Riboflavin also helps the body metabolise iron, a key process for making energy.

Chondroitin for flexible cartilage

Found naturally in joint cartilage, tendons and ligaments, chondroitin is where collagen fibres are embedded. Chondroitin tends to absorb water, which adds to the thickness and elasticity of the collagen. Chondroitin is also believed to destroy harmful enzymes that are responsible for breaking down cartilage in joint tissues.

Customer testimonials

Catharine B

Have noticed a significant difference in my energy levels

I have been taking Fighting Fatigue for just over two weeks and in the last few days have noticed a significant difference in my energy levels. I have felt tired for years so am amazed by the result.

James M

Highly recommended this product

More energy and highly recommended this product I have been taking for almost three years when I first seen them on the QVC shopping tv. While I had been another supplement and it was good I though I would try Prime Fifty and I felt a bit more lively with these. The delivery was very good considering the time we are in. Cheers

Mr Richardson

I highly recommend them

I have been using these for over a year, if i dont take any for a couple of days my joints feel tight and sore. I highly recommend them

FAQ

For honest help and advice, our award-winning team is here Monday to Friday from 9am to 5pm.

Freephone 0800 107 5995

From outside the UK
+44 (0) 1223 750 874

Do you ship overseas?

Yes, we ship all over the world. Shipping costs will apply.

How long until I feel a benefit?

This can vary from person to person, and also depends on the product and the benefit you're looking for. Supplements aren't pharmaceutical drugs, and they won't have an immediate effect.

Some supplements work in the background, delivering long-term health benefits without noticeable short-term differences.

But for most products, the active ingredient in your supplement needs to build up to sufficient levels in the body to begin to have an effect. In general, you should notice a benefit after 4-8 weeks of supplementation.

If you have a question about a specific product, please contact our Customer Care team for more detailed advice. hello@primefifty.com

I’m taking prescribed medication. Can I still take supplements?

If you’re taking any medication or are under medical supervision, please make sure that you consult a doctor or pharmacist before taking any supplements.

How do your subscriptions work and how do I pay for them?

Our subscriptions are designed to make life easier and ensure you never run out of your supplements.

Once subscribed, your order is automatically processed and delivered based on your chosen schedule – every 28 days.

Payments are processed automatically at the start of each subscription cycle, so you don’t need to worry about reordering manually.

You’ll receive a 3-day reminder before each shipment, and our subscriptions are fully flexible – you can amend, pause, or cancel at any time to suit your needs.

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Why Prime Fifty?

We believe ageing isn’t about limitation. It’s about supporting your body to stay capable, active, capable and independent. Prime Fifty is here to help you live the life you want to live.

Learn more

What your body needs after 50 that it didn't need before

Living longer sounds good, but living well is what matters. Discover how your nutritional needs change after 50 and what the science says about maintaining strength, clarity and resilience.

Learn more

Discover our Healthy Ageing Blend

As well as targeted support for your health goals, most Prime Fifty supplements also include our Healthy Ageing Blend – extra vitamins, minerals and nutrients that help to build a strong foundation for your health as you age.

Learn More

ENERGISED & ACTIVE

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